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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MYBL2
All Species:
12.42
Human Site:
S251
Identified Species:
21.03
UniProt:
P10244
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P10244
NP_002457.1
700
78764
S251
E
L
A
A
A
T
T
S
K
E
Q
E
P
I
G
Chimpanzee
Pan troglodytes
XP_514658
769
86303
S251
E
L
A
A
A
T
T
S
K
E
Q
E
P
I
S
Rhesus Macaque
Macaca mulatta
XP_001084853
700
78675
S251
E
P
A
A
A
T
T
S
K
E
Q
E
P
I
P
Dog
Lupus familis
XP_534424
883
97262
S434
E
A
T
A
A
T
T
S
K
E
Q
G
A
V
P
Cat
Felis silvestris
Mouse
Mus musculus
P48972
704
79084
K251
A
I
A
A
T
S
A
K
E
L
G
H
E
P
V
Rat
Rattus norvegicus
NP_001100006
704
79549
K251
A
A
V
A
T
T
S
K
E
H
K
Q
E
P
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511778
753
85883
P257
A
S
A
F
I
Q
Q
P
I
V
D
D
D
P
D
Chicken
Gallus gallus
Q03237
686
77718
I229
V
P
N
W
P
V
D
I
S
E
I
K
E
E
D
Frog
Xenopus laevis
P52551
743
82891
E251
P
G
I
R
S
E
Q
E
S
G
G
E
G
S
N
Zebra Danio
Brachydanio rerio
NP_001003867
633
70853
S210
T
D
T
E
E
L
L
S
E
E
V
E
I
S
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_797351
686
76826
G258
V
R
T
L
Y
P
M
G
H
D
T
L
G
Q
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P20024
340
36221
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9S7G7
776
86488
Q255
S
Q
S
T
N
D
L
Q
D
E
V
Q
R
G
N
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
O13493
324
36522
Conservation
Percent
Protein Identity:
100
88
98.2
72.5
N.A.
85.2
87.7
N.A.
38.3
72.5
54.2
52.1
N.A.
N.A.
N.A.
N.A.
37.8
Protein Similarity:
100
89.7
98.7
74.7
N.A.
89.4
91.3
N.A.
54.5
81.5
69
65.8
N.A.
N.A.
N.A.
N.A.
54
P-Site Identity:
100
93.3
86.6
60
N.A.
13.3
13.3
N.A.
6.6
6.6
6.6
20
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
93.3
86.6
66.6
N.A.
33.3
40
N.A.
13.3
13.3
13.3
26.6
N.A.
N.A.
N.A.
N.A.
6.6
Percent
Protein Identity:
N.A.
20.1
N.A.
25.5
N.A.
20.7
Protein Similarity:
N.A.
31.8
N.A.
40.8
N.A.
29.5
P-Site Identity:
N.A.
0
N.A.
6.6
N.A.
0
P-Site Similarity:
N.A.
0
N.A.
20
N.A.
0
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
22
15
36
43
29
0
8
0
0
0
0
0
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% C
% Asp:
0
8
0
0
0
8
8
0
8
8
8
8
8
0
22
% D
% Glu:
29
0
0
8
8
8
0
8
22
50
0
36
22
8
0
% E
% Phe:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
8
0
0
0
0
0
8
0
8
15
8
15
8
8
% G
% His:
0
0
0
0
0
0
0
0
8
8
0
8
0
0
0
% H
% Ile:
0
8
8
0
8
0
0
8
8
0
8
0
8
22
0
% I
% Lys:
0
0
0
0
0
0
0
15
29
0
8
8
0
0
0
% K
% Leu:
0
15
0
8
0
8
15
0
0
8
0
8
0
0
0
% L
% Met:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
8
0
8
0
0
0
0
0
0
0
0
0
15
% N
% Pro:
8
15
0
0
8
8
0
8
0
0
0
0
22
22
15
% P
% Gln:
0
8
0
0
0
8
15
8
0
0
29
15
0
8
0
% Q
% Arg:
0
8
0
8
0
0
0
0
0
0
0
0
8
0
0
% R
% Ser:
8
8
8
0
8
8
8
36
15
0
0
0
0
15
8
% S
% Thr:
8
0
22
8
15
36
29
0
0
0
8
0
0
0
0
% T
% Val:
15
0
8
0
0
8
0
0
0
8
15
0
0
8
15
% V
% Trp:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _